P J F M Merkus Selected Research

dornase alfa (Pulmozyme)

12/2011	Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation.
2/2008	Recombinant human deoxyribonuclease for the treatment of acute asthma in children.

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P J F M Merkus Research Topics

Disease

6	Asthma (Bronchial Asthma) 11/2016 - 02/2002
2	Cystic Fibrosis (Mucoviscidosis) 01/2016 - 12/2011
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2016
1	Inflammation (Inflammations) 12/2015
1	Acquired Immunodeficiency Syndrome (AIDS) 12/2011
1	Airway Obstruction (Choking) 12/2011
1	Glycogen Storage Disease Type II (Pompe's Disease) 12/2010
1	Bronchiolitis 02/2002
1	Infections 02/2002
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 02/2002
1	Meningococcal Infections 02/2002
1	Sudden Infant Death (SID) 02/2002

Drug/Important Bio-Agent (IBA)

3	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2015 - 06/2004
2	dornase alfa (Pulmozyme)FDA Link 12/2011 - 02/2008
1	Volatile Organic CompoundsIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2015
1	AcidsIBA 12/2010
1	GlucosidasesIBA 12/2010
1	Expectorants (Mucolytics)IBA 02/2008
1	Deoxyribonucleases (DNase)FDA Link 02/2008
1	Bronchodilator Agents (Bronchodilators)IBA 02/2008
1	Pharmaceutical PreparationsIBA 02/2008
1	SmokeIBA 02/2002
1	Tobacco Smoke Pollution (Passive Smoking)IBA 02/2002

Therapy/Procedure

1	Precision Medicine 11/2016
1	Enzyme Therapy 12/2010
1	Therapeutics 02/2008